Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC STF-31 | 724741-75-7 | 99.8% | 423.53 | 5 MG
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STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC50 of 1 μM. It is also a NAMPT inhibitor and inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells.
- Selective inhibitor of glucose transporter 1 (GLUT1).
- NAMPT inhibitor.
- Inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells.
- Specifically toxic to RCC4 cells at concentrations of 0.01-10 μM, while RCC4/VHL cells are relatively unaffected.
- Causes necrotic cell death and does not induce autophagy, apoptosis, or DNA damage at concentrations of 1.25-5 μM for 3 days.
- Reduces light-induced CX3CR1gfp/+ mice microglial activation and retinal degeneration in vivo at 10 mg/kg.
- Promotes accumulation of necrotic thymocytes after Dexamethasone-induced apoptosis in vivo at 10 mg/kg.
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eMolecules 90800-42-3 | 8-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | MFCD18417146 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc(O)c2ncccc2c1 | 0.25g | 528983323
8-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | 90800-42-3 | MFCD18417146 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc(O)c2ncccc2c1 | 0.25g | 528983323
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000723573 TAMRA AMINE 5-ISOME 25MG
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Medchemexpress LLC Sulfo-EGS 10mg | 167410-92-6 | 10 MG
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Sulfo-EGS is a water-soluble, homobifunctional, amine-reactive crosslinker used to covalently link proximal primary amines in proteins and peptides to map interactions and probe complex topology. It is provided for research use in small milligram quantities.
- Water-soluble homobifunctional amine-reactive crosslinker.
- Targets primary amines for covalent crosslinking of proteins and peptides.
- Facilitates mapping of protein-protein and protein-peptide interactions.
- Suitable for small-scale, solution-phase crosslinking experiments.
- Available in milligram pack sizes for research applications.
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eMolecules 1255942-06-3 | DBCO-amine | Target Molecule | MFCD22380759 | 276.339 | C18H16N2O | 0.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 5mg | 662702331
DBCO-amine | Target Molecule | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 0.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 5mg | 662702331
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000743358 ISOQUINOLIN-1-AMINE 10G
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Selleck Chemical LLC Bemnifosbuvir Hemisulfate-5MG
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Bemnifosbuvir Hemisulfate (AT-527 RG-6422 RO 7496998) is a hemi-sulfate salt of AT-511 AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0 47 M
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Oakwood Chemicals | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 250mg | 480128099
7-Bromoisoquinoline | Oakwood Chemicals | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 250mg | 480128099
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000744403 MPEG-AMINE MW 10000 250MG
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Synthonix - Stock | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 100mg | 525910352
7-Bromoisoquinoline | Synthonix - Stock | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 100mg | 525910352
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Medchemexpress LLC Capsaicin | 404-86-4 | MFCD00017259 | 305.41 g·mol^-1 | C18H27NO3 | 200 MG
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Capsaicin is a naturally occurring capsaicinoid and a potent TRPV1 agonist derived from chili peppers. Supplied for research and analytical applications, it is commonly used to model nociception and to study pain, inflammation, and related signaling pathways. CAS 404-86-4; formula C18H27NO3; molar mass 305.41 g·mol-1.
- Activates TRPV1 for receptor pharmacology studies.
- Useful in pain, inflammation, and nociception models.
- Applicable to in vitro biochemical and cell-based assays.
- Provided as a small pack suitable for analytical and research use.
- Well characterized with established chemical identifiers for traceability.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000746035 CR-1-31-B 10MM/1ML
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Medchemexpress LLC 3-(N-maleimido-propionylamino)-propyl-sulfonic acid sodium salt | 185332-92-7 | MFCD17215919 | 98.8% | 382.28 g·mol⁻¹ | C12H11N2NaO9S | 25 MG
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Sulfo-GMBS is a water-soluble, heterobifunctional cross-linker bearing a sulfo-NHS ester reactive toward primary amines and a maleimide reactive toward sulfhydryl groups. It enables efficient amine-to-thiol conjugation in aqueous buffers for protein and peptide modification, labeling, and cross-linking workflows. The sodium sulfonate improves aqueous solubility for biological applications.
- Water-soluble heterobifunctional cross-linker for amine-to-thiol coupling
- Contains a sulfo-NHS ester reactive toward primary amines
- Contains a maleimide group selective for sulfhydryl groups
- Suitable for conjugation in aqueous buffers and physiological conditions
- High purity supports consistent conjugation performance
- Applicable to protein labeling, cross-linking, and bioconjugation assays
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Medchemexpress LLC Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt | 185332-92-7 | MFCD17215919 | 98.8% | 382.28 g/mol | C12H11N2NaO9S | 1 ML
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Sulfo-GMBS is a water-soluble, heterobifunctional cross-linker that links primary amines to sulfhydryl groups via a non-cleavable maleimide spacer. Supplied as a ready-to-use 10 mM solution in DMSO or as a solid, it is intended for protein and peptide conjugation, immobilization, and labeling in biochemical and assay workflows.
- Water-soluble amine-thiol cross-linker suitable for protein and peptide conjugation.
- Provides a short, non-cleavable spacer facilitating stable linkage between functional groups.
- Available as a 10 mM solution in DMSO or in solid form for flexible use.
- High purity (approximately 98.8%) supports reproducible conjugation reactions.
- Soluble in DMSO at 50 mg/mL (≈130.8 mM) for easy preparation of working solutions.
- Recommended storage: solid at -20°C sealed; in solvent at -80°C for extended stability.
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Apexbio Technology LLC Diosmetin 520-34-3 200mg
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Diosmetin (CAS 520-34-3) is a small molecule flavonoid that functions as an agonist of the aryl hydrocarbon receptor (AHR) a ligand-activated transcription factor involved in the regulation of xenobiotic-metabolizing enzymes In cell-based studies diosmetin dose-dependently increases AHR-mediated transcriptional activation including upregulation of CYP1A1 mRNA and enzymatic activity in MCF-7 cells The compound demonstrates inhibitory effects on CYP1A1 enzyme activity with an IC50 of approximately 30 nM in microsomal assays Diosmetin is utilized in biomedical research to study AHR activation CYP1 enzyme regulation and related cellular responses such as viability and gene expression changes
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